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Interleukin 8 Receptor Beta / IL8RB (CXCR2) Antibody

Interleukin 8 Receptor Beta / IL8RB (CXCR2) Antibody

Manufacturer	Abbexa
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human
Isotype	IgG
Applications	WB
Amount	200 ul
Host	Rabbit
Item no.	abx002121-200
Targets	CXCL8;;CXCR2
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	Interleukin 8 Receptor Beta / IL8RB (CXCR2)
Description	CXCR2 Antibody is a Rabbit Polyclonal antibody against CXCR2. The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration.
Conjugation	Unconjugated
Purification	Affinity purified.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P25025
UniProt Entry Name	CXCR2_HUMAN
Gene Symbol	CXCR2
Gene ID	3579
Molecular Weight	Calculated MW: 40 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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