Melanophilin (MLPH) Antibody

Melanophilin (MLPH)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

MLPH Antibody is a Rabbit Polyclonal antibody against MLPH. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

MLPH

Purified by affinity chromatography.