Glutaminyl tRNA Synthetase (QARS) Antibody

Glutaminyl tRNA Synthetase (QARS)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

QARS Antibody is a Rabbit Polyclonal antibody against QARS. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

QARS

Purified by affinity chromatography.