F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody

F-Box And WD Repeat Domain Containing 11 (FBXW11)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

PBS containing 0.09% sodium azide.

FBXW11

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse FBXW11.