Fc Fragment Of IgA Receptor / CD89 (FCAR) Antibody

Fc Fragment Of IgA Receptor / CD89 (FCAR)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

PBS containing 0.09% sodium azide.

FCAR

Purified through a protein A column, followed by peptide affinity purification.