Desmoglein 3 (DSG3) Antibody

Desmoglein 3 (DSG3)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

PBS containing 0.09% sodium azide.

DSG3

Purified through a protein A column, followed by peptide affinity purification.