Minichromosome Maintenance Deficient 6 Homolog (MCM6) Antibody

Minichromosome Maintenance Deficient 6 Homolog (MCM6)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

PBS containing 0.09% sodium azide.

This product is for research use only.

MCM6_HUMAN