Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2) Antibody

Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes shaker, shaw, shab, and shal have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.

PBS containing 0.09% sodium azide.

KCNA2

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse, Rat and Rabbit KCNA2.