POU Class 3 Homeobox 2 (POU3F2) Antibody

POU Class 3 Homeobox 2 (POU3F2)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).

PBS containing 0.09% sodium azide.

POU3F2

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse and Rat POU3F2.