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Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) Antibody

Rap Guanine Nucleotide Exchange Factor 5 (RAPGEF5) Antibody

Manufacturer	Abbexa
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human
Isotype	IgG
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	abx029260-400
Targets	SOS1
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	RAPGEF5
Description	Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).
Conjugation	Unconjugated
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92565
UniProt Entry Name	RPGF5_HUMAN
Buffer	PBS containing 0.09% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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