EIF4EBP1 (pT36) Antibody

EIF4EBP1 (pT36)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. It is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

PBS containing 0.09% sodium azide.

This product is for research use only.

4EBP1_HUMAN