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FRAP1 (pT2446) Antibody

FRAP1 (pT2446) Antibody

Item no.	abx031982-400
Manufacturer	Abbexa
Amount	400 ul
Quantity options	400 ul 80 ul
Category	Oncology Antibodies By Cell Type Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Cell Biology Cell Status Autophagy Primary Antibodies Dot Blot
Type	Antibody Primary
Format	Liquid
Applications	ELISA, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FRAP1 (phospho-Thr2446)
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	FRAP1 (pT2446)
Storage Conditions	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 289 kDa
Description	FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Dry Ice	No
Buffer	PBS containing 0.09% sodium azide.
Clonality	Polyclonal
Note	This product is for research use only.
Purification	Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
UniProt Entry Name	MTOR_HUMAN
Manufacturer - Specificity	Predicted to react with Mouse and Rat MTOR.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/16/2025

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