Gastric Inhibitory Polypeptide Receptor (GIPR) Antibody

Gastric Inhibitory Polypeptide Receptor (GIPR)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

PBS containing 0.09% sodium azide.

This product is for research use only.

GIPR_HUMAN