Peroxisome Assembly Protein 12 (PEX12) Antibody

Peroxisome Assembly Protein 12 (PEX12)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.

PBS containing 0.09% sodium azide.

PEX12

Purified through a protein A column, followed by peptide affinity purification.

Predicted to react with Mouse and Cow PEX12.