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Cytochrome P450 2A6 (CYP2A6) Antibody

Cytochrome P450 2A6 (CYP2A6) Antibody

Manufacturer	Abbexa
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse
Isotype	IgG
Applications	WB, IHC
Amount	100 ul
Host	Rabbit
Item no.	abx004456-100
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	CYP2A6
Description	CYP2A6 Antibody is a Rabbit Polyclonal antibody against CYP2A6. This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
Conjugation	Unconjugated
Purification	Affinity purified.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P11509
UniProt Entry Name	CP2A6_HUMAN
Gene Symbol	CYP2A6
Gene ID	1548
Molecular Weight	Calculated MW: 56 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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