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Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

Manufacturer	Abbexa
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse
Isotype	IgG
Applications	WB
Amount	80 ul
Host	Rabbit
Item no.	abx033769-80
Targets	PAK4
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	PAK4
Description	PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Conjugation	Unconjugated
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O96013
UniProt Entry Name	PAK4_HUMAN
Buffer	PBS containing 0.09% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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