Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody

Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

ARHGEF7 Antibody is a Rabbit Polyclonal antibody against ARHGEF7. Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

ARHGEF7

Purified by affinity chromatography.