Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7) Antibody

Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

PTPN7 Antibody is a Rabbit Polyclonal antibody against PTPN7. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

PTPN7

Purified by affinity chromatography.