B-cell Lymphoma 6 (BCL6) Antibody

B-cell Lymphoma 6 (BCL6)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

BCL6 Antibody is a Rabbit Polyclonal antibody against BCL6. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.

BCL6

Purified by affinity chromatography.