Phospholipase C Delta 3 (PLCD3) Antibody

Phospholipase C Delta 3 (PLCD3)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca (2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq].

PBS containing 0.09% sodium azide.

PLCD3

Purified through a protein A column, followed by peptide affinity purification.