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SEN2 Polyclonal Antibody

SEN2 Polyclonal Antibody

Manufacturer	Abbkine Scientific
Category	Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	ELISA, Western Blot
Amount	200ul
Host	Rabbit
Item no.	ABK-ABP60365-200ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	Synthesized peptide derived from part region of human SEN2 protein
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Purification	The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	TSEN2 (TRNA Splicing Endonuclease Subunit 2) is a Protein Coding gene. Diseases associated with TSEN2 include Pontocerebellar Hypoplasia Type 2B and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Gene Expression and tRNA processing. TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in TSEN2 have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for TSEN2.
Gene ID	80746
Alternative	tRNA-splicing endonuclease subunit Sen2; tRNA-intron endonuclease Sen2; HsSen2
Other info	The antibody detects endogenous levels of SEN2 protein
Accession	Q8NCE0

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ul

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Delivery expected until 6/13/2024