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Cytokeratin 8 (phospho Ser73) Polyclonal Antibody

Cytokeratin 8 (phospho Ser73) Polyclonal Antibody

Item no.	ABK-ABP50297-30ul
Manufacturer	Abbkine Scientific
Amount	30 ul
Quantity options	100 ul 200 ul 30 ul
Category	Oncology Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Primary Antibodies Intermediate filaments By Organ Bladder Cancer
Type	Antibody Polyclonal
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	KRT8,CYK8,Keratin,type II cytoskeletal 8,Cytokeratin-8,CK-8,Keratin-8,K8,Type-II keratin Kb8
Available
Manufacturer - Applications	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Shipping Temperature	Gel pack with blue ice.
Storage Conditions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background	KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in KRT8 cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for KRT8.
Formulation	Liquid solution
Immunogen	Synthesized peptide derived from human Cytokeratin 8 around the phosphorylation site of S73
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration	1 mg/ml
Other information	Phospho-Cytokeratin 8 (S73) Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at S73.
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 30 ul

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Delivery expected until 12/18/2025

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