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Girdin (phospho Ser1417) Polyclonal Antibody

Girdin (phospho Ser1417) Polyclonal Antibody

Item no.	ABK-ABP55749-200ul
Manufacturer	Abbkine Scientific
Amount	200 ul
Quantity options	100 ul 200 ul 30 ul
Category	Oncology Antibodies By Cell Type Immunohistochemistry ELISA Primary Antibodies Astrocytoma
Type	Antibody Polyclonal
Applications	IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CCDC88A,APE,GRDN,KIAA1212,Girdin,Akt phosphorylation enhancer,APE,Coiled-coil domain-containing protein 88A,G alpha-interacting vesicle-associated protein,GIV,Girders of actin filament,Hook-related protein 1,HkRP1
Available
Manufacturer - Applications	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
Shipping Temperature	Gel pack with blue ice.
Storage Conditions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Background	CCDC88A (coiled-coil domain containing 88A) encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of CCDC88A and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Formulation	Liquid solution
Immunogen	Synthesized peptide derived from human Girdin around the phosphorylation site of S1417
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration	1 mg/ml
Other information	Phospho-Girdin (S1417) Polyclonal Antibody detects endogenous levels of Girdin protein only when phosphorylated at S1417.
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ul

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Delivery expected until 1/1/2026

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