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Caldesmon (phospho Ser789) Polyclonal Antibody

Caldesmon (phospho Ser789) Polyclonal Antibody

Manufacturer	Abbkine Scientific
Category	Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	ELISA, Immunofluorescence, Western Blot, Immunohistochemistry
Amount	200ul
Host	Rabbit
Item no.	ABK-ABP50520-200ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen	Synthesized peptide derived from human Caldesmon around the phosphorylation site of S789
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms.
Gene ID	800
Alternative	CALD1; CAD; CDM; Caldesmon; CDM
Other info	Phospho-Caldesmon (S789) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S789.
Accession	Q05682

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABK-ABP50520-200ul-datasheet.pdf

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Amount: 200ul

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Delivery expected until 6/13/2024