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Neurofibromin Polyclonal Antibody

Neurofibromin Polyclonal Antibody

Item no.	ABK-ABP51931-200ul
Manufacturer	Abbkine Scientific
Amount	200ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	ELISA, Immunofluorescence, Western Blot
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Immunogen	Synthesized peptide derived from the Internal region of human Neurofibromin at AA range: 1520-1600
Applications notes	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Formulation	Liquid solution
Concentration	1 mg/ml
Storage buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions	Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping	Gel pack with blue ice.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	NF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.
Gene ID	4763
Alternative	NF1; Neurofibromin; Neurofibromatosis-related protein NF-1
Other info	Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
Accession	P21359

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ul

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Delivery expected until 10/30/2025

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