ENT1 Polyclonal Antibody

Gel pack with blue ice.

SLC29A1 is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Synthesized peptide derived from the N-terminal region of human ENT1

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

ENT1 Polyclonal Antibody detects endogenous levels of ENT1 protein.