L-Selectin Polyclonal Antibody

Gel pack with blue ice.

SELL encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The selectin L contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Synthesized peptide derived from the Internal region of human L-Selectin

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

L-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein.