hnRNP DL Polyclonal Antibody

Gel pack with blue ice.

HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by HNRNPDL has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for HNRNPDL. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by HNRNPDL are similar to its family member HNRPD.

Synthesized peptide derived from the Internal region of human hnRNP DL at AA range: 210-290

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

hnRNP DL Polyclonal Antibody detects endogenous levels of hnRNP DL protein.