Alpha-Methylacyl-CoA Racemase (AMACR) Antibody

Primary Antibodies

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

AMACR Antibody is a Rabbit Polyclonal antibody against AMACR. This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

AMACR

Purified by affinity chromatography.