Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) Antibody

Primary Antibodies

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

TRADD Antibody is a Rabbit Polyclonal antibody against TRADD. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.

TRADD

Purified by affinity chromatography.