Glutamate Decarboxylase 2 (GAD2) Antibody

Glutamate Decarboxylase 2 (GAD2)

Store at -20 °C. Avoid repeated freeze/thaw cycles.

Glutamate Decarboxylase 2 (GAD2) Antibody is a Rabbit Polyclonal against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Prior to lyophilization: 1% BSA and 0.02% NaN3.

GAD2

Purified by antigen affinity column chromatography.

138275