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Aprepitant

Aprepitant

Manufacturer	Adooq
Category	Food Safety Drugs Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	A10083-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Short Description	Aprepitant is classified as an NK1 antagonist. Aprepitant has been shown to inhibit both the acute and delayed emesis induced by cytotoxic chemotherapeutic drugs by blocking substance P landing on receptors in the brains neurons. It has also been shown to increase the activity of the 5-HT3 receptor antagonists ondansetron and the corticosteroid dexamethasone, which are also used to prevent nausea and vomiting caused by chemotherapy.
Cas No	170729-80-3
Synonyms	MK0869, MK-869, L-754030, Emend
Formula	C23H21F7N4O3
Solubilty	DMSO
Purity	>98%
Chemical Name	5-([(2R, 3S)-2-((R)-1-[3, 5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluorophenyl) morpholino]methyl)-1H-1, 2, 4-triazol-3(2H)-one
M. Wt.	534, 4
SMILES	C[C@ H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@ @ H]2[C@ @ H](N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F
Storage	2 years at -20C

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Amount: 5mg

available

Delivery expected until 5/23/2024