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Astemizole 100mg

Astemizole 100mg

Item no.	A13899-100
Manufacturer	Adooq
CASRN	68844-77-9
Amount	100 mg
Quantity options	10 mg 100 mg 10mM x 1mL in DMSO 25 mg 5 mg 50 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98%
Smiles	COC1=CC=C(C=C1)CCN2CCC(CC2)NC3=NC4=CC=CC=C4N3CC5=CC=C(C=C5)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Astemisan, Hismanal, Histamen, Paralergim
Similar products	68844-77-9
Available
Storage Conditions	2 years at -20C
Molecular Weight	458, 57
Chemical Name	1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine
Description	Astemizole is a potent antihistamine (H1-receptor antagonist, IC50 = 4 nM) that displays selectivity over dopamine, 5-HT, and muscarinic acetylcholine receptors. This compound has shown potent hERG K+ channel blocking activity (IC50 = 0.9 nM), antimalarial activity in multidrug resistant strains in vitro (IC50 = 227 - 734 nM), and has been used as a chaperone to correct folding defects and restore protein function for some mutated forms of hERG channels.
Solubilty	DMSO

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

A13899-100-datasheet.pdf

A13899-100-safety-datasheet.pdf