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Anti-P-Glycoprotein (MDR)

Anti-P-Glycoprotein (MDR)

Manufacturer	American Research Products
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Specific against	other
Isotype	IgG1
Applications	ICC
Amount	100 ug
Host	Mouse
Item no.	ARP-10-M1060
eClass 6.1	32160702
eClass 9.0	42030590
Available
Background	P-Glycoprotein, , also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette tra nsporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Immunogen	A mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Form	Lyophilized
Specificity	Human. No cross reactivity with other proteins.
Storage	2-8C. For long term -20C after reconstitution.
Synonyms	CLCS, MDR1, P-GP, PGY1, ABC20, CD243, GP170, ATP-binding cassette sub-family B member 1, P-glycoprotein 1
References	1. Callen, D. F., Baker, E., Simmers, R. N., Seshadri, R., Roninson, I. B. : Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. Hum. Genet. 77: 142-144, 1987. 2. de Lannoy, I. A. M., Silverman, M. : The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem. Biophys. Res. Commun. 189: 551-557, 1992.
Reconstitution	1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 6/20/2024