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Protease-Activated Receptor-1, PAR-1 Antagonist 2, amide

Protease-Activated Receptor-1, PAR-1 Antagonist 2, amide

Item no.	AS-65487
Manufacturer	AnaSpec
Amount	1 mg
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Cardiovascular Research Thrombosis & Hemostasis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Conjugate/Tag	Unconjugated
Purity	Peak Area by HPLC ≥95%
Sequence	Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2
Citations	Fujita, T. et al. J Biochem 126, 174 (1999).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Protease Activated Receptor 1,PAR 1,PAR 1 Antagonist,PAR 1 Antagonist Amide
Shipping Condition	Room temperature
Available
Manufacturer - Category	Catalog Peptides / Catalog Peptides Gr / Peptides
Manufacturer - Targets	Protease-Activated Receptor (PAR)
Shipping Temperature	RT
Storage Conditions	- 20 °C
Molecular Weight	893
Manufacturer - Research Area	Cardiovascular Research; Cell Signaling / Coagulation; GPCR
Description	This peptide is a PAR-1 antagonist which inhibited SFLLRNP induced platelet aggregation with an IC50 of 115 uM. Antagonists specific for the thrombin receptor can be promising compounds for treatment of thrombosis.
Sequence One-Letter Code	S-F(para-Fluoro)-Aad-LRNP-NH2
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535134020

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-65487-safety-datasheet.pdf