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MMP-1 (Catalytic Domain), human recombinant

MMP-1 (Catalytic Domain), human recombinant

Item no.	AS-55575-1
Manufacturer	AnaSpec
Amount	1 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	other
Host	E.coli
Conjugate/Tag	Unconjugated
Purity	≥95% by SDS-PAGE
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Dry ice
Available
Manufacturer - Type	Catalog recombinant
Manufacturer - Applications	Protease activity
Manufacturer - Category	Catalog Recombinant Proteins / Catalog Recombinant / Proteins
Manufacturer - Targets	Matrix Metalloproteinase (MMP), MMP-1
Shipping Temperature	Dry Ice
Storage Conditions	Store at -80°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	17.5 kDa
Manufacturer - Research Area	Adhesion & Extracellular Matrix; Cancer & Apoptosis / Tissue Remodeling/MMPs; Oncogenesis
Description	Matrix metalloproteinases (MMP’s) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-1 (collagenase-1) is involved in tumor development and metastasis and rheumatoid arthritis. It is proposed as a therapeutic target for these diseases. MMP-1 digests a broad range of substrates, including ?-1 antitrypsin, myelin basic protein, collagen I, II, III, VII, VIII, casein, gelatin, and others - The sequence (Accession # NP_002412) corresponding to the catalytic domain (aa 106-261) of Human MMP-1 was expressed in E. coli. The recombinant human MMP-1 was purified from bacterial lysate and refolded using proprietary technique. The molecular weight of the recombinant Human MMP-1 Catalytic Domain is ~17.5 kDa.
Purification Method	Purified
Concentration	lot dependent
Storage Buffer	300 mM NaCl, 20 mM Tris-HCl, 10 mM CaCl2, 1 µM ZnCl2, pH=7.5
Manufacturer - Specificity	Catalytic domain (aa 106-261) of Human MMP-1
Post Synthesis Coupling	No
Usage	Research use
UNSPSC	12352202
GTIN	5400535007157

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-55575-1-safety-datasheet.pdf