Goat anti-LRRK2 / PARK8 (near C Terminus) Antibody

Goat anti-LRRK2 / PARK8 (near C Terminus) Antibody
Principle Name: LRRK2 / PARK8 (near C Terminus)
Official Symbol: LRRK2
All Name and Symbols: LRRK2; PARK8; ROCO2; FLJ45829; DKFZp434H2111; leucine-rich repeat kinase 2; dardarin; Parkinson disease (autosomal dominant) 8; AURA17; DARDARIN; RIPK7; augmented in rheumatoid arthritis 17
Accession Number(s): NP_940980.3
Peptide Sequence: CELAEKMRRTSV, is from internal region (near the C Terminus)
Human Gene ID(s): 120892
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB, IHC, ICC, IEM
Peptide ELISA: antibody detection limit dilution 1 to 64000.
Western Blot: This product has been successfully used in Western blot for human brain as described in the following paper: Sharma et al, Neuropathol Appl Neurobiol. 2011 Jun 23, PMID 21696411. Recommended concentration: 0.3-1ug/ml.
Immunohistochemistry: In paraffin embedded Human Brain (Hippocampus) shows staining of neuronal cytoplasm. Recommended concentration: 1-2ug/ml. Paraffin embedded Human Brain (Cortex). Recommended concentration: 2ug/ml. This product has been successfully
Reference(s): Paisan-Ruiz C, Jain S, Evans EW, Gilks WP, Simon J, van der Brug M, de Munain AL, Aparicio S, Gil AM, Khan N, Johnson J, Martinez JR, Nicholl D, Carrera IM, Pena AS, de Silva R, Lees A, Marti-Masso JF, Perez-Tur J, Wood NW, Singleton AB. Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease. Neuron. 2004 Nov 18; 44(4):595-600. .PMID: 15541308