Goat anti-Silver homologue / Pmel 17 (C-terminus) Antibody

Goat anti-Silver homologue / Pmel 17 (C-terminus) Antibody
Principle Name: Silver homologue / Pmel 17 (C-terminus)
Official Symbol: SILV
All Name and Symbols: silver homolog (mouse) ; PMEL17; SILV ; D12S53E; ME20; SI; SIL; gp100 ; Melanocyte protein mel 17; Pmel 17; Silver, mouse, homolog of; silver (mouse homolog) like; silver (mouse homolog)-like; silver homolog
Accession Number(s): NP_008859.1
Peptide Sequence: CPIGENSPLLSGQQ, is from C Terminus
Human Gene ID(s): 6490
Non-Human GeneID(s): 20431 (mouse); 362818 (rat);
Important Comments:
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 128000.
Western Blot: Approx 26kDa band observed in Human Skin lysates, corresponding to the M-beta fragment of the precursor protein (Leonhardt et al, Mol Biol Cell. 2013 Apr; 24(7):964-81.PMID: 23389629). Calculated MW of 70.3kDa according to NP_008859.1. Prima
Reference(s): Fowler DM, Koulov AV, Alory-Jost C, Marks MS, Balch WE, Kelly JW. Functional amyloid formation within mammalian tissue. PLoS Biol. 2006 Jan; 4(1):e6. .PMID: 16300414