Description |
Goat anti-CYBB / GP91-PHOX Antibody Principle Name: CYBB / GP91-PHOX Official Symbol: CYBB All Name and Symbols: CYBB; cytochrome b-245, beta polypeptide (chronic granulomatous disease); CGD; GP91-1; GP91-PHOX; GP91PHOX; NOX2; cytochrome b-245, beta polypeptide Accession Number(s): NP_000388.2 Peptide Sequence: SYLNFARKRIKNP, is from internal region Human Gene ID(s): 1536 Non-Human GeneID(s): Important Comments: Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. Applications: Pep ELISA, IHC Tested Species: Human Peptide ELISA: antibody detection limit dilution 1 to 64000. Immunohistochemistry: In paraffin embedded Human Placenta shows staining of syncytiotrophoblasts. Recommended concentration, 1-2ug/ml. Reference(s): Zhu C, Lindsey S, Konieczna I, Eklund EA. Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation. J Leukoc Biol. 2008 Mar; 83(3):680-91..PMID: 18089853 |