Goat anti-PCSK9 (aa164-175) Antibody

Goat anti-PCSK9 (aa164-175) Antibody
Principle Name: PCSK9 (aa164-175)
Official Symbol: PCSK9
All Name and Symbols: PCSK9; proprotein convertase subtilisin/kexin type 9 ; FH3; HCHOLA3; NARC-1; NARC1 ; hypercholesterolemia, autosomal dominant 3; neural apoptosis regulated convertase 1
Accession Number(s): NP_777596.2
Peptide Sequence: PRYRADEYQPPD, is from internal region
Human Gene ID(s): 255738
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB Trf
Peptide ELISA: antibody detection limit dilution 1 to 32000.
Western Blot: In transfected HEK293 transiently expressing full-length Human PCSK9 (myc and DYKDDDDK tagged), a doublet of approx. 80-100kDa was observed. No bands were observed in mock-transfected HEK293 and the same bands were observed using anti-myc t
Reference(s): Lalanne F, Lambert G, Amar MJ, Chetiveaux M, Zair Y, Jarnoux AL, Ouguerram K, Friburg J, Seidah NG, Brewer HB Jr, Krempf M, Costet P. Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells. J Lipid Res. 2005 Jun; 46(6):1312-9. Epub 2005 Mar 1. .PMID: 15741654