Goat anti-TGFBR1 (aa50-63) Antibody

Pep ELISA, WB, IHC

Goat anti-TGFBR1 (aa50-63) Antibody
Principle Name: TGFBR1 (aa50-63)
Official Symbol: TGFBR1
All Name and Symbols: TGFBR1; transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK-5; ALK5; LDS1A; LDS2A; SKR4; TGFR-1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; activin A receptor type II-like kinase, 53kD; activin A receptor typ
Accession Number(s): NP_004603.1; NP_001124388.1
Peptide Sequence: TDGLCFVSVTETTD, is from internal region
Human Gene ID(s): 7046
Non-Human GeneID(s): 21812 (mouse); 29591 (rat);
Important Comments: This antibody is expected to recognize both reported isoforms (NP_004603.1; NP_001124388.1). The immunizing peptide represents part of a potential extracellular domain.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.Peptide ELISA: antibody detection limit dilution 1 to 64000.
Western Blot: Approx 55kDa band observed in Rat Liver lysates (calculated MW of 55.6kDa according to Rat NP_036907.2). Recommended concentration: 0.1-0.3ug/ml.
Immunohistochemistry: Paraffin embedded Human Adrenal Gland. Recommended concentration: 5ug/ml.
Reference(s): Yu N, Kozlowski JM, Park II, Chen L, Zhang Q, Xu D, Doll JA, Crawford SE, Brendler CB, Lee C. Overexpression of transforming growth factor ß1 in malignant prostate cells is partly caused by a runaway of TGF-ß1 auto induction mediated through a defective recruitment of protein phosphatase 2A by TGF-ß type I receptor. Urology. 2010 Dec; 76(6):1519.e8-13.PMID: 21030067