Mouse Monoclonal Antibody to KSHV ORF8

Enterez GeneID: 4961501
General Information: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi¿s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman¿s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Immunogen: Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. ;
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Rabbit anti-serum.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000
References: 1.Pennacchio, L, Science 2001. 294, 169-173. ; 2.Prieur, X. J Biol Chem 2003. 278, 25468-25480. ;