Mouse Monoclonal Antibody to ApoM

Mouse IgG2a

MW: 21kDa
Enterez GeneID: 55937
General Information: ApoM (apolipoprotein M, also designated G3a or NG20), with 188-amino acid protein(about 21kDa), is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in the specific binding of cellular receptors, the regulation of lipolytic enzymes, and the process of lipid exchange. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes, and remains associated with the microsomes after carbonate treatment. Apo-M is expressed in liver and kidney, and is secreted into the bloodstream in HDLs, and also found in triglyceride-rich lipoproteins and LDLs.
Immunogen: Purified recombinant fragment of ApoM expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; ICC: 1 to 200 - 1 to 1000
References: 1. Xu, N. & Dahlback, B. 1999 J. Biol. Chem. 274:31286 ; 2. Duan J, Dahlback B, Villoutreix BO.FEBS Lett. 2001 Jun 15; 499(1-2):127-32. ; 3. Xu, N., Nilsson-Ehle, P. & Ahren, B. 2004. J. Nutr.Biochem. 15 (10):579-582 ; 4. Zhang, X.Y. , et al.2004. Acta Histochem. 106 (2):123-128 ;