Mouse Monoclonal Antibody to HER-2

Mouse IgG2b

Enterez GeneID: 2064
General Information: The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis
Immunogen: Purified recombinant fragment of HER-2 expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000
References: 1. Sho E., et al. Arterioscler Thromb Vasc Biol. 2004: 24: 1916-21. ; 2. Satterthwaite, A.B., et al. Genomics.1992:12:788-794.; 3. Krause, D.S., et al. 1994. Blood.84: 691-701.;