Mouse Monoclonal Antibody to CD20

Mouse IgG

Enterez GeneID: 931
General Information: CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
Immunogen: Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20, conjugated to KLH.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; IHC: 1 to 200 - 1 to 1000; ICC: 1 to 200 - 1 to 1000
References: 1. Villegas J. Cell Tissue Res. 2004, Mar, 315(3):349-59. Epub 2004 Jan 15. ; 2. Metelitza DI. Karasyova EI. Grintsevich EE. et al. J Inorg Biochem. 2004, Jan, 98(1):1-9. ;