Mouse Monoclonal Antibody to EhpB1

Mouse IgG1

MW: 110kDa
Enterez GeneID: 2047
General Information: EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.
Immunogen: Purified recombinant fragment of EphB1 (aa19-133) expressed in E. Coli. ;
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000
References: 1. J Clin Invest. 2002 Oct; 110(8):1141-50. ; 2. J Biol Chem. 2002 Feb 8; 277(6):3823-8. Epub 2001 Nov 16. ; 3. J Biol Chem. 2003 Mar 21; 278(12):10150-6. Epub 2003 Jan 6. ; 4. Biochem Biophys Res Commun. 2006 Feb 3; 340(1):268-76.