Mouse Monoclonal Antibody to PBEF1

Mouse IgG1

Enterez GeneID: 10135
General Information: PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Immunogen: Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide.
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000
References: 1. Cancer Res. 2005 Dec 15; 65(24):11259-64. ; 2. J Histochem Cytochem. 2006 Feb; 54(2):161-9. ; 3. Int Arch Allergy Immunol. 2006; 139(4):306-16.