Mouse Monoclonal Antibody to HSP90AA1

Mouse IgG1

MW: 90kDa
Enterez GeneID: 3320
General Information: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
Immunogen: Purified recombinant fragment of human HSP90AA1 expressed in E. Coli. ;
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400
References: Mol Biol Cell. 2009 Apr; 20(7):1916-25. ; J Cell Sci. 2009 Aug 15; 122(Pt 16):2996-3004. ;