Mouse Monoclonal Antibody to PIK3R1

Mouse IgG1

MW: 83.6kDa
Enterez GeneID: 5295
General Information: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.
Immunogen: Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; FCM: 1 to 200 - 1 to 400
References: 1.Cancer Epidemiol Biomarkers Prev. 2011 May; 20(5):923-33. 2.Cancer Res. 2010 Jul 1; 70(13):5305-15.