Description |
Catalog Number: sAP-1007 Product Name: Mouse Monoclonal Antibody to MRPL42 Target Molecle: MRPL42 Aliases: L31MT; L42MT; S32MT; MRPL31; MRPS32; PTD007; RPML31; HSPC204; MRP-L31; MRP-L42; MRP-S32 Species: Human; MW: 16.6kDa Enterez GeneID: 28977 General Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q. ; Immunogen: Purified recombinant fragment of human MRPL42 (AA: 10-142) expressed in E. Coli. Clone: MM3H6H2; Isotype: Mouse IgG1 Size and Concentration: 100ug/1mg/ml Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide. Reconstitution and Storage: Reconstitued with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage. Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000; FCM: 1 to 200 - 1 to 400 References: 1. Cell Death Differ. 2012 Apr; 19(4):616-22. ; 2. Biochem Biophys Res Commun. 2011 Aug 12; 411(4):832-7. ; |